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  1. Content type: Research

    To examine the effect of the natural antimicrobial peptide human β-defensin-3 (hBD-3), on the migration of a head and neck cancer cell line in vitro using microfabrication and soft-lithographic techniques.

    Authors: Kevin Wang, Joanne H Wang, Harihara Baskaran, Russell Wang and Rick Jurevic

    Citation: Head & Neck Oncology 2012 4:41

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  2. Content type: Research

    Thyroid carcinoma generally responds well to treatment and spinal metastasis is an uncommon feature. Many studies have looked at the management of spinal metastasis and proposed treatments, plans and algorithm...

    Authors: Sami Ramadan, Mohamed A Ugas, Richard J Berwick, Manisha Notay, Hyongyu Cho, Waseem Jerjes and Peter V Giannoudis

    Citation: Head & Neck Oncology 2012 4:39

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  3. Content type: Case report

    Secondary malignancy in the oral mucosa is recognized as one of the most serious complications in patients who received allogenic hematopoietic stem cell transplantation (HSCT). However, potential risk factors...

    Authors: Yasumasa Kakei, Masaya Akashi, Hideki Komatsubara, Tsutomu Minamikawa and Takahide Komori

    Citation: Head & Neck Oncology 2012 4:38

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  4. Content type: Research

    As a result of major ablative surgery, head and neck oncology patients can be left with significant defects in the orofacial region. The resultant defect raises the need for advanced reconstruction techniques....

    Authors: Ramin Carbiner, Waseem Jerjes, Kaveh Shakib, Peter V Giannoudis and Colin Hopper

    Citation: Head & Neck Oncology 2012 4:37

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  5. Content type: Research

    The incidence of head and neck cancer is relatively low in developed countries and highest in South East Asia. Notwithstanding advances in surgery and radiotherapy over the past several decades, the 5-year sur...

    Authors: Gregory M Trilling, Hyongyu Cho, Mohamed A Ugas, Samerah Saeed, Asia Katunda, Waseem Jerjes and Peter Giannoudis

    Citation: Head & Neck Oncology 2012 4:36

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  6. Content type: Case report

    The present study summarizes our experience in treating a patient with a suspected granulocyte colony-stimulating factor (G-CSF)-producing squamous cell carcinoma (SCC) of the lower gingiva, which is a rather ...

    Authors: Jun-ichi Kobayashi, Akihiro Miyazaki, Takashi Yamamot, Kenji Nakamori, Rina Suzuki, Takeshi Kaneko, Naohiro Suzuki and Hiroyoshi Hiratsuka

    Citation: Head & Neck Oncology 2012 4:35

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  7. Content type: Research

    The management of cervical lymph node metastases from an unknown primary tumor remains a controversial subject. Recently, Positron Emission Tomography (PET) has proved useful in the detection of these tumors, ...

    Authors: Gabriel Pereira, Joaquim Castro Silva and Eurico Monteiro

    Citation: Head & Neck Oncology 2012 4:34

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  8. Content type: Case report

    Burkitt’s lymphoma is a highly aggressive lymphoma. The endemic form is present with Epstein - Barr virus. The most common sites are the mandible, facial bones, kidneys, gastrointestinal tract, ovaries, breast...

    Authors: Tahwinder Upile, Waseem Jerjes, Jesuloba Abiola, Panagiotis Kafas, Ann Sandison, Zaid Hamdoon, Mohammed Al-Khawalde and Hani Radhi

    Citation: Head & Neck Oncology 2012 4:33

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  9. Content type: Review

    We briefly highlight the growing body of recent evidence linking unprotected oral sex with the development of some types of head and neck cancer in younger patients. These tumours appear to be increasing in in...

    Authors: Tahwinder Upile, Waseem Jerjes, Mohammed Al-Khawalde, Hani Radhi and Holger Sudhoff

    Citation: Head & Neck Oncology 2012 4:31

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  10. Content type: Research

    Squamous cell carcinoma mainly afflicts patients older than 40 years of age however, few cases are seen in younger patients. The aim of this study therefore was to determine the incidence of squamous cell carc...

    Authors: Samuel E Udeabor, Majeed Rana, Gerd Wegener, Nils-Claudius Gellrich and André M Eckardt

    Citation: Head & Neck Oncology 2012 4:28

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  11. Content type: Case report

    The thyroid gland is a known but an unusual site for metastatic tumors from various primary sites. Despite the fact that it is one of the largest vascular organs in the body, clinical and surgical cases have g...

    Authors: Mohamed T Hafez, Mohamed A Hegazy, Khaled Abd Elwahab, Mohammad Arafa, Islam Abdou and Basel Refky

    Citation: Head & Neck Oncology 2012 4:27

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  12. Content type: Research

    Neurilemmomas are benign tumors deriving from Schwann cells of the nerve sheath. They occur in all parts of the body. The highest incidence of neurilemmoma is in the head and neck region (38–45%), but involvem...

    Authors: Jing Hu, Yang-Yang Bao, Ke-Jia Cheng, Shui-Hong Zhou, Ling-Xiang Ruan and Zhou-Jun Zheng

    Citation: Head & Neck Oncology 2012 4:26

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  13. Content type: Case report

    Although pilomatrixomas are frequently encountered by dermatologists and pathologists in the differential diagnosis of head and neck lesions, this is not usually the case among head and neck surgeons.

    Authors: Tahwinder Upile, Waseem Jerjes, Fabian Sipaul, Ann Sandison, Panagiotis Kafas, Mohammed Al-Khawalde and Hani Radhi

    Citation: Head & Neck Oncology 2012 4:25

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  14. Content type: Research

    Cystic lesions within the parotid gland are uncommon and clinically they are frequently misdiagnosed as tumours. Many theories have been proposed as to their embryological origin. A 20-year retrospective revie...

    Authors: Tahwinder Upile, Waseem Jerjes, Mohammed Al-Khawalde, Panagiotis Kafas, Steve Frampton, Angela Gray, Bruce Addis, Ann Sandison, Nimesh Patel, Holger Sudhoff and Hani Radhi

    Citation: Head & Neck Oncology 2012 4:24

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  15. Content type: Research

    Perioperative blood transfusion is associated with reduced prognosis in a number of solid malignancies. We investigate its role in a head & neck squamous cell cancer (HNSCC) cell lines. Growth of these cell li...

    Authors: Tahwinder Upile, Waseem Jerjes, Sandeep Singh, Mohammed Al-Khawalde, Zaid Hamdoon, Hani Radhi and Colin Hopper

    Citation: Head & Neck Oncology 2012 4:22

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  16. Content type: Research

    Advanced and recurrent cutaneous squamous cell carcinoma of the scalp and forehead require aggressive surgical excision often resulting in complex defects requiring reconstruction. This study evaluates various...

    Authors: Larissa Sweeny, Brendan Eby, J Scott Magnuson, William R Carroll and Eben L Rosenthal

    Citation: Head & Neck Oncology 2012 4:21

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  17. Content type: Review

    Salivary gland cancers are very rare tumors. They are characterized by a histologic heterogeneity and a poor outcome. According to this rarity, few prospective data are available to date. No standard recommend...

    Authors: Aymen Lagha, Nesrine Chraiet, Mouna Ayadi, Sarra Krimi, Bassem Allani, Hela Rifi, Henda Raies and Amel Mezlini

    Citation: Head & Neck Oncology 2012 4:19

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  18. Content type: Research

    Head and neck cancers are of particular interest to health care providers, their patients, and those paying for health care services, because they have a high morbidity, they are extremely expensive to treat, ...

    Authors: Jed J Jacobson, Joel B Epstein, Frederick C Eichmiller, Teresa B Gibson, Ginger S Carls, Emily Vogtmann, Shaohung Wang and Barbara Murphy

    Citation: Head & Neck Oncology 2012 4:15

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  19. Content type: Research

    Several factors have been identified to affect morbidity and mortality in oral cancer patients. The time taken to process a resected cancer specimen in a patient presenting with primary or recurrent disease ca...

    Authors: Waseem Jerjes, Tahwinder Upile, Hani Radhi, Aviva Petrie, Aidan Adams, Jacqueline Callear, Panagiotis Kafas and Colin Hopper

    Citation: Head & Neck Oncology 2012 4:14

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  20. Content type: Review

    Clear cell chondrosarcoma is a rare variant of chondrosarcoma that mostly involves the end of long bones. However, nine cases have been reported in the head and neck: four in larynx, two in nasal septum, two i...

    Authors: Sepideh Mokhtari and Abbas Mirafsharieh

    Citation: Head & Neck Oncology 2012 4:13

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  21. Content type: Research

    Stereotactic body radiation therapy (SBRT) has seen increasing use as a salvage strategy for selected patients with recurrent, previously-irradiated squamous cell carcinoma of the head and neck (rSCCHN). PET-C...

    Authors: Kyle Wang, Dwight E Heron, John C Flickinger, Jean-Claude M Rwigema, Robert L Ferris, Gregory J Kubicek, James P Ohr, Annette E Quinn, Cihat Ozhasoglu and Barton F Branstetter

    Citation: Head & Neck Oncology 2012 4:12

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  22. Content type: Research

    Oral cancer accounts for roughly 3% of cancer cases in the world with about 350,000 newly reported cases annually and a 5-year survival rate of only 50%. Majority of oral cancers are squamous cell carcinomas t...

    Authors: Nyla Dil and Abhijit G Banerjee

    Citation: Head & Neck Oncology 2012 4:11

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  23. Content type: Case report

    Hemangiopericytoma (HPC) is a rare tumor of uncertain malignant potential arising from mesenchymal cells with pericytic differentiation. It accounts for 3-5% of soft tissue sarcomas and 1% of vascular tumors. ...

    Authors: Muhammad Mohsin Fareed, Abdullah Suleiman Mazaed Al Amro, Rashad Akasha, Mansour Al Assiry, Mushabbab Al Asiri, Mutahir Tonio and Yasser Bayoumi

    Citation: Head & Neck Oncology 2012 4:10

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  24. Content type: Research

    The objective of this study was to evaluate the efficacy of Nimesulide, a selective cyclooxygenase-2 (COX-2) inhibitor, on the growth of hypopharyngeal carcinoma cells (FaDu) in vitro, and investigate its pote...

    Authors: Tian Jia-Jun, Lu Su-Mei, Yu Liang, Ma Ju-Ke, Mu Ya-Kui, Wang Hai-Bo and Xu Wei

    Citation: Head & Neck Oncology 2012 4:7

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  25. Content type: Research

    The use of tobacco is known to increase the incidence of developing oral cancer by 6 times, while the additive effect of drinking alcohol further increases the risk leading to higher rate of morbidity and mort...

    Authors: Waseem Jerjes, Tahwinder Upile, Hani Radhi, Aviva Petrie, Jesuloba Abiola, Aidan Adams, Panagiotis Kafas, Jacqueline Callear, Ramin Carbiner, Kartic Rajaram and Colin Hopper

    Citation: Head & Neck Oncology 2012 4:6

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  26. Content type: Research

    Accurate clinical staging of oral squamous cell cancer can be quite difficult to achieve especially if nodal involvement is identified. Radiologically-assisted clinical staging is more accurate and informs the...

    Authors: Waseem Jerjes, Tahwinder Upile, Hani Radhi, Aviva Petrie, Jesuloba Abiola, Aidan Adams, Jacqueline Callear, Panagiotis Kafas, Syedda Abbas, Kartic Rajaram and Colin Hopper

    Citation: Head & Neck Oncology 2012 4:5

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  27. Content type: Case report

    The etiology of Inflammatory myofibroblastic tumor(IMT) is contentious. In this study, we used computed tomography (CT) to examine tonsillar IMT and further analyzed the etiology of this entity.

    Authors: Yun-Zhen Luo, Li-Bo Dai, Shui-Hong Zhou, Xing-Mei Luo, Jun Fan and Ling-Xiang Ruan

    Citation: Head & Neck Oncology 2012 4:4

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  28. Content type: Research

    In thyroid surgery vessel division and haemostasis make up an important and time consuming part of the operation. While the presence of the recurrent laryngeal nerve limits the liberal use of diathermia, the m...

    Authors: Anandi HW Schiphorst, Bas A Twigt, Sjoerd G Elias and Thijs van Dalen

    Citation: Head & Neck Oncology 2012 4:2

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  29. Content type: Research

    Taking intraoperative frozen sections (FS) is a widely used procedure in oncologic surgery. However so far no evidence of an association of FS analysis and premalignant changes in the surgical margin exists. T...

    Authors: Stefan Gerber, Carole Gengler, Klaus W Grätz and Astrid L Kruse

    Citation: Head & Neck Oncology 2011 3:56

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  30. Content type: Research

    Vascuologenesis is the de novo establishment of blood vessels and vascular networks from mesoderm-derived endothelial cell precursors (angioblasts). Recently a novel mechanism, by which some genetically deregu...

    Authors: Tahwinder Upile, Waseem Jerjes, Hani Radhi, Mohammed Al-Khawalde, Panagiotis Kafas, Seyed Nouraei and Holger Sudhoff

    Citation: Head & Neck Oncology 2011 3:55

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  31. Content type: Review

    There is a paucity of publications detailing how to deal with the difficult thyroid cancer. When compared to other cancers, it is relatively rare with several histopathological subtypes which run differing cli...

    Authors: Tahwinder Upile, Waseem Jerjes, Jaspal Mahil, Hitesh Tailor, Ramkishan Balakumar, Anuja Rao, Yassar Qureshi, Iain Bowman and Suchana Mukhopadhyay

    Citation: Head & Neck Oncology 2011 3:54

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  32. Content type: Review

    Traditionally, in the United Kingdom and Europe, the surgeon was generally not troubled by litigation from patients presenting as elective as well as emergency cases, but this aspect of custom has changed. Lit...

    Authors: Waseem Jerjes, Jaspal Mahil and Tahwinder Upile

    Citation: Head & Neck Oncology 2011 3:52

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  33. Content type: Research

    The submental flap is gaining popularity as a simple technique for reconstruction of small to moderate size defects of the oral cavity. However, its role in composite defects involving the jaw is not clearly d...

    Authors: Ayman A Amin, Mostafa A Sakkary, Ashraf A Khalil, Mohammmed A Rifaat and Sherif B Zayed

    Citation: Head & Neck Oncology 2011 3:51

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