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Table 5 Rates of failure and impact of PET-CT planning vs. non-PET-CT planning on failure

From: A retrospective, deformable registration analysis of the impact of PET-CT planning on patterns of failure in stereotactic body radiation therapy for recurrent head and neck cancer

 

Overall Cohort (n = 96)

Definitive SBRT Subgroup (n = 89)

 

Total

PET-CT

Non-PET-CT

p (X2)*

Total

PET-CT

Non-PET-CT

p (X2)*

 

Number of patients:

96

45

51

 

89

45

44

  

Failure vs. No Failure:

  % No Failure (n)

51% (49)

62% (28)

41% (21)

0.044

49% (44)

62% (28)

36% (16)

0.020

 

  % Overall (Any) Failure (n)

49% (47)

38% (17)

59% (30)

0.044

51% (45)

38% (17)

64% (28)

0.020

 

Type of Failure:

  % In-field (n)

7% (7)

11% (5)

4% (2)

0.247

8% (7)

11% (5)

5% (2)

0.434

 

  % Overlap (n)

15% (14)

11% (5)

18% (9)

0.401

16% (14)

11% (5)

20% (9)

0.258

 

  % Marginal (n)

22% (21)

13% (6)

29% (15)

0.083

22% (20)

13% (6)

32% (14)

0.045

 

  % Regional/Distant (n)

16% (15)

13% (6)

18% (9)

0.588

16% (14)

13% (6)

18% (8)

0.573

 

Combined Failure Categories:

  % In-field/Overlap/Marginal (n)

43% (41)

33% (15)

51% (26)

0.100

45% (40)

33% (15)

57% (25)

0.034

 

  % Overlap/Marginal (n)

36% (35)

24% (11)

47% (24)

0.033

38% (34)

24% (11)

52% (23)

0.009

 
  1. Abbreviations: SBRT = stereotactic body radiation therapy, *Chi-square comparison of PET-CT vs. non-PET-CT planning.