Table 1 Patient cohort characteristics

1,250

11.0

2,167

19.0

2,372

20.8

2,304

20.2

3,310

29.0

11,403

100.0

Gender (Male)

726

58.1

1,267

58.5

1,436

60.5

1,717

74.5

2,813

85.0

7,959

69.8

Age group

18-44

72

5.8

213

9.8

159

6.7

230

10.0

86

2.6

760

6.7

45-64

328

26.2

1,062

49.0

1,221

51.5

1,459

63.3

1,499

45.3

5,569

48.8

65+

849

67.9

892

41.2

991

41.8

615

26.7

1,725

52.1

5,072

44.5

Geographic location

North East

96

7.7

109

5.0

167

7.0

160

6.9

280

8.5

812

7.1

North West

214

17.1

332

15.3

447

18.8

399

17.3

548

16.6

1,940

17.0

Merseyside

0

0.0

0

0.0

0

0.0

0

0.0

0

0.0

0

0.0

Yorkshire and

Humber

121

9.7

225

10.4

276

11.6

256

11.1

375

11.3

1,253

11.0

East Midlands

112

9.0

212

9.8

245

10.3

244

10.6

269

8.1

1,082

9.5

West Midlands

92

7.4

206

9.5

228

9.6

170

7.4

300

9.1

996

8.7

East of England

147

11.8

204

9.4

185

7.8

207

9.0

304

9.2

1,047

9.2

London

134

10.7

280

8.3

291

12.3

269

11.7

431

13.0

1,305

11.4

South East

169

13.5

338

15.6

279

11.8

289

12.5

437

13.2

1,512

13.3

South West

156

12.5

225

10.4

209

8.8

272

11.8

302

9.1

1,164

10.2

Scotland

1

0.1

4

0.2

4

0.2

2

0.1

0

0.0

11

0.1

No fixed above

0

0.0

2

0.1

0

0.0

3

0.1

2

0.1

7

0.1

Wales

6

0.5

9

0.4

12

0.5

16

0.7

13

0.4

56

0.5

Foreign (including

Isle of Man and

Channel Islands)

1

0.0

18

0.8

21

0.9

14

0.6

40

1.2

93

0.8

Unknown

1

0.0

3

0.1

8

0.3

3

0.1

8

0.2

22

0.2

Northern Ireland

0

0.0

0

0.0

0

0.0

0

0.0

1

0.0

1

0.0

Mean

SD

Mean

SD

Mean

SD

Mean

SD

Mean

SD

Mean

SD

Age

69.6

13.9

61.8

13.7

62.8

12.5

58.3

11.1

65.4

10.7

63.2

12.6

Length of follow-up (months)

34.9

16.9

31.4

18.3

30.8

18.5

30.1

18.3

30

18.7

31

18.4