From: The association between EGFR variant III, HPV, p16, c-MET, EGFR gene copy number and response to EGFR inhibitors in patients with recurrent or metastatic squamous cell carcinoma of the head and neck
P16 IHC positive
P16 IHC negative
HPV PCR positive
10
5
P = 0.0016
HPV PCR negative
25
(Chi-Square)
HPV ISH positive
6
0
P = 0.0002
HPV ISH negative
7
31
(Fisher's)