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Table 1 Clinical characteristics of the entire study cohort (n = 53)

From: The association between EGFR variant III, HPV, p16, c-MET, EGFR gene copy number and response to EGFR inhibitors in patients with recurrent or metastatic squamous cell carcinoma of the head and neck

Clinical Characteristic

 

Number

Median Age (Range)

 

56 (15-78)

Gender

Female:Male

12:41

ECOG Performance Status

0:1:2

15:34:4

Locoregional Recurrence

Yes:No

45:8

Distant Metastases

Yes:No

19:34

Primary Tumor Site

Oropharynx

20

 

Larynx

14

 

Oral cavity

10

 

Hypopharynx

2

 

Neck mass unknown

4

 

Paranasal sinus

3

Histologic Grade

Well differentiated

5

 

Moderately differentiated

33

 

Poorly differentiated

14

 

Infiltrating basaloid

1

Prior Therapy

Chemotherapy

21

 

Radiation Therapy

51

 

Surgery

41

Race

Asian

8

 

Black

42

 

Caucasian

9

 

Other

1

Smoker

Current

33

 

Former

3

 

Never

15

 

Unknown

2

Erlotinib

Yes: No

35:18

Best Response

Partial response

4

 

Stable disease

20

 

Progressive disease

24

 

Inevaluable

5