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Fiber-based microendoscopic multiphoton imaging

We developed a multiphoton microscope which integrates an all normal dispersion fiber laser, a double cladding photonic crystal fiber and a MEMS mirror scanner based hand-held probe. The fiber laser has a central wavelength of 1.06um,a repetition rate of 76MHz and maximum average output power of more than 1W. The MEMS mirror based probe is compact and Second harmonic generation and two photon excited fluorescence images of biological sample were demonstrated.

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Correspondence to Gangjun Liu.

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Open Access This article is published under license to BioMed Central Ltd. This is an Open Access article is distributed under the terms of the Creative Commons Attribution 2.0 International License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Liu, G., Kieu, K., Wise, F.W. et al. Fiber-based microendoscopic multiphoton imaging. Head Neck Oncol 2, O35 (2010). https://doi.org/10.1186/1758-3284-2-S1-O35

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Keywords

  • Photonic Crystal
  • Fiber Laser
  • Harmonic Generation
  • Photonic Crystal Fiber
  • Average Output Power