| |
C-survivin*
|
N-survivin†
|
|---|
| |
Low, n(%)
|
High, n(%)
|
P-value
|
Low, n(%)
|
High, n(%)
|
P-value
|
|---|
|
Histological growth pattern
| | | | | | |
|
Tubular, cribriform
|
6(100)
|
24(77.4)
|
0.255
|
12 (85.7)
|
18(78.3)
|
0.459
|
|
Solid
|
0(0)
|
7(22.6)
| |
2(14.3)
|
5(21.7)
| |
|
Grade
| | | | | | |
|
Well, moderately
|
5(83.3)
|
22(71.0)
|
0.475
|
12 (85.7)
|
15(65.2)
|
0.164
|
|
Poorly
|
1(16.7)
|
9(29.0)
| |
2(14.3)
|
8(34.8)
| |
|
Stage
| | | | | | |
|
I, II
|
4(66.7)
|
15(48.4)
|
0.357
|
10(71.4)
|
9(39.1)
|
0.357
|
|
III, IV
|
2(33.3)
|
16(51.6)
| |
2(28.6)
|
14(51.6)
| |
|
Tumor size
| | | | | | |
|
≤ 3 cm
|
5(83.3)
|
9(34.6)
|
0.043‡
|
8(61.5)
|
11(42.1)
|
0.057
|
|
> 3 cm
|
1(16.7)
|
17(65.4)
| |
5(38.5)
|
8(57.9)
| |
|
Lymph node involvement
| | | | | | |
|
Negative
|
6(100)
|
27(87.1)
|
0.476
|
6(46.2)
|
11(87)
|
0.821
|
|
Positive
|
0(0)
|
4(10.8)
| |
7(53.8)
|
3(13)
| |
|
Bcl-2
| | | | | | |
|
Negative
|
5(83.3)
|
13(41.9)
|
0.078
|
10(71.4)
|
8(34.8)
|
0.031‡
|
|
Positive
|
1(16.7)
|
18(58.1)
| |
4(28.6)
|
15(65.2)
| |
|
Ki-67
| | | | | | |
|
Negative
|
6(100)
|
27(87.1)
|
0.476
|
13(92.9)
|
20(87)
|
0.509
|
|
Positive
|
0(0)
|
4(12.9)
| |
1(7.1)
|
3(13)
| |
|
P53
| | | | | | |
|
Negative
|
5(83.3)
|
23(74.2)
|
0.543
|
12(85.7)
|
16(69.6)
|
0.267
|
|
Positive
|
1(16.7)
|
8(25.8)
| |
2(14.3)
|
7(30.4)
| |
- * cytoplasmic survivin
- † nuclear survivin
- ‡ statistically significant (P < 0.05)
