Background
Optical biopsy systems have been investigated for various clinical applications; however the main interest is in the diagnosis of premalignant lesions.
The aim of this study was to compare findings of optical coherence tomography (OCT) with histopathology of various oral lesions to see if this technique could be used as an adjunct or alternative to histopathology in assessing oral dysplasia. The technique is a non-invasive interferometric tomographic imaging modality which allows millimetre penetration with micrometer-scale axial and lateral resolution.