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Table 2 Subgroup analysis of treatment outcome after stereotactic radiosurgery or radiotherapy for local failures of nasopharyngeal carcinoma

From: Comparison of single versus fractionated dose of stereotactic radiotherapy for salvaging local failures of nasopharyngeal carcinoma: a matched-cohort analysis

 

3-year local failure-free rate

3-year overall survival rate

 

SRS

SRM

p value

SRS

SRM

p value

Sex

      

   male

54%

87%

0.006

63%

63%

0.806

   female

42%

73%

0.275

75%

24%

0.067

Age

      

   ≤ 45

27%

87%

0.023

63%

44%

0.338

   > 45

49%

80%

0.028

67%

62%

0.702

Type of failure

      

   persistent disease

77%

94%

0.456

87%

90%

0.589

   recurrent disease

30%

75%

0.001

52%

35%

0.419

rT stage

      

   rT1

69%

88%

0.133

85%

79%

0.721

   rT2-4

28%

78%

0.006

45%

28%

0.458

Tumor volume

      

   ≤ 5 cc

62%

90%

0.219

79%

75%

0.502

   > 5 – 10 cc

61%

67%

0.342

78%

44%

0.117

   > 10 cc

69%

84%

0.106

25%

52%

0.108

  1. SRS: stereotactic radiotherapy using single fracton
  2. SRM: stereotactic radiotherapy using multiple fractions