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Table 2 Subgroup analysis of treatment outcome after stereotactic radiosurgery or radiotherapy for local failures of nasopharyngeal carcinoma

From: Comparison of single versus fractionated dose of stereotactic radiotherapy for salvaging local failures of nasopharyngeal carcinoma: a matched-cohort analysis

  3-year local failure-free rate 3-year overall survival rate
  SRS SRM p value SRS SRM p value
Sex       
   male 54% 87% 0.006 63% 63% 0.806
   female 42% 73% 0.275 75% 24% 0.067
Age       
   ≤ 45 27% 87% 0.023 63% 44% 0.338
   > 45 49% 80% 0.028 67% 62% 0.702
Type of failure       
   persistent disease 77% 94% 0.456 87% 90% 0.589
   recurrent disease 30% 75% 0.001 52% 35% 0.419
rT stage       
   rT1 69% 88% 0.133 85% 79% 0.721
   rT2-4 28% 78% 0.006 45% 28% 0.458
Tumor volume       
   ≤ 5 cc 62% 90% 0.219 79% 75% 0.502
   > 5 – 10 cc 61% 67% 0.342 78% 44% 0.117
   > 10 cc 69% 84% 0.106 25% 52% 0.108
  1. SRS: stereotactic radiotherapy using single fracton
  2. SRM: stereotactic radiotherapy using multiple fractions