Table 1 Previously published case reports (2000-2012) of primary squamous cell carcinoma of thyroid
From: Primary squamous cell carcinoma of thyroid: a case report and review of literature
Author [Ref] | Gender/Age | Presentation | Stage | Associated Problem | Treatment given | Survival | Comments |
|---|---|---|---|---|---|---|---|
Zimmer PW [1] | Female/64 years | Asymptomatic neck mass | T2N0M0 | - | Total thyroidectomy | 7 months | - |
Kebapci N [7] | Female/25 years | Right neck mass | T4N1M0 | Hashimotos' thyroiditis | |||
Papillary carcinoma | Total thyroidectomy and RAI therapy | 44 months | - | ||||
Ko YS [8] | Male/87 years | Asymptomatic neck mass | T4N0M0 | - | Right lobectomy | NA | CK5/6 + CK19 + EMA,p53 focal + BRAF mutation + |
Mercante G [9] | Male/67 years | - | T2N0M0 | Follicular carcinoma | Lobe-isthmusectomy + Adjuvant chemoradiation | 2 years | - |
De Vos FY [10] | - | Neck mass | T4N0M0 | - | Induction chemotherapy (Cisplatin + paclitaxel) | ||
Total thyroidectomy | 20 months | Induction chemotherapy resulted in R0 resection | |||||
Yucel H [11] | Male/88 years | Neck mass | T4N0M0 | Hyperthyroidism | Total thyroidectomy Adjuvant radiation therapy | 6 months | Patient RAI therapy 20 years back |
Eorn TI [12] | Female/43 years | Neck mass | T3N0M0 | Papillary carcinoma | Total thyroidectomy Adjuvant radiation therapy 59.4 Gy And RAI | 8 months | CK7 + p 63 + |
Makay O [13] | Male/53 years Male/71 years | Neck mass, hoarse voice and weight loss | T3N0M0 | - | Near total thyroidectomy Chemoradiation 50 Gy + Doxorubicin and cyclophosphamide | 2 months 4 months 5 months | - |
Fassan M [17] | Female/64 years | Neck mass | T3N0M0 | Goiter | Total thyroidectomy | NA | CK 5/6 + CK 7 + CK 19 + |
Maamouri F [18] | Female/87 years | Right neck mass | T3N0M0 | Papillary carcinoma | Total thyroidectomy And RAI therapy | 6 months | - |
Chintamani [14] | Female/50 years Male/60 years Male/58 years | Dysphagia, hoarse voice and stridor | T4N0M0 | Hyperthyroidism | Total thyroidectomy Adjuvant radiotherapy 50 Gy | 12 months | - |
Jung TS [15] | Male/56 years | Neck mass, hoarse voice | T3N0M0 | Follicular carcinoma | Total thyroidectomy Adjuvant radiotherapy 50 Gy | 8 years | - |
Sutak J [19] | Female/80 years | Asymptomatic neck mass | T4N1M0 | Tall cell variant papillary carcinoma | Total thyroidectomy | - | CK 7 + CK 19 + CK AE1/3 + P53 focal + |
Zhou XH [16] | 4 patients | NA | T4N0M0 | - | Total thyroidectomy Adjuvant radiotherapy 50 Gy + chemotherapy | 4 months 6 months 13 months 26 months | Longer survival was seen in combined trimodality treatment |
Lam KY [20] | 4 females/71 years | Neck mass, stridor | T4N0M0 | - | Total thyroidectomy | 4 months | CK 7 + CK 19 + CK AE1/3 + P53 focal + |
Kleer CG [21] | 7 females/1 male 31-90 years | Neck mass | T4N0M0 | Tall cell variant papillary carcinoma | Total thyroidectomy | 6 Months- 48 months | - |
Jones JM [22] | Male/48 years | Hoarse voice, left neck mass | T4N1M0 | - | Total thyroidectomy and LND | 8 months | - |