Table 5 Patients with carcinoma ex pleomorphic adenoma as primary head and neck cancer
Author, year | Patient no. | Patient age | Primary site, grade | Primary stage | Intervention for primary site | Location of spinal metastasis | Time frame of spinal metastasis | Signs + symptoms of spinal metastasis | Intervention for spinal metastasis | Outcome | Other metastasis | Mortality | Cause of death |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Thomas, 1965 [30] | 1 | 74 | Parotid carcinoma ex pleomorphic adenoma | - | Excision, removal of recurrences | T7 | 8 yr | Weakness, back pain, increased micturition | Laminectomy | No response | None | 9 d | GI haemorrhage, benign gastric ulcer |
2 | 63 | Parotid carcinoma ex pleomorphic adenoma | - | Excision, adjuvant RT, removal of recurrences | T8 | 26 yr | Back pain, complete paralysis | Laminectomy | Paralysis persisted, died soon after op | - | No time given | - | |
Manoj-Thomas, 2006 [13] | 3 | 58 | Parotid carcinoma ex pleomorphic adenoma | - | Superficial parotidectomy | L4 | 7 yr | Low back pain with radiation to left leg | RT | Improved pain. Hypoaesthesia at 18 mo | Left acetabulum, Lungs | - | - |
Ye, 2007 [12] | 4 | 28 | Submandibular carcinoma ex pleomorphic adenoma | - | - | T10, L3 | 40 yr | Leg weakness | Excision, RT (25 Gy) | Improved, no recurrence on follow-up MRI | Forearm skin, scalp, frontal bone, occipital bone, lungs | - | - |