Table 4 Descriptive interpretation of OCT image changes. KL: keratin cell layer, EP: epithelium, BM: basement membrane, LP: lamina propria. Increase: ↑, decrease: ↓, no change: ↔
From: Structural validation of oral mucosal tissue using optical coherence tomography
Pathology entity | KL hyper-reflective | KL hypo-reflective | KL normo-reflective | Not applicable | EP ↑ | EP ↓ | EP ↔ | EP not identified | BM demarcated | BM non-demarcated | Not applicable | LP homogenous | LP non-homogenous |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Keratosis (n = 5) | 5 | 0 | 0 | 0 | 1 | 0 | 4 | 0 | 5 | 0 | 0 | 5 | 0 |
Benign oral lesions (n = 14) | 2 | 0 | 9 | 3 | 1 | 1 | 11 | 1 | 11 | 2 | 1 | 12 | 2 |
Oral dysplasia (n = 30) | 13 | 4 | 10 | 3 | 25 | 0 | 3 | 2 | 27 | 1 | 2 | 26 | 4 |
Carcinoma in situ (n = 4) | 1 | 1 | 2 | 0 | 4 | 0 | 0 | 0 | 4 | 0 | 0 | 4 | 0 |
Invasive carcinoma (n = 25) | 10 | 10 | 5 | 0 | 25 | 0 | 0 | 0 | 1 | 24 | 0 | 0 | 25 |
Normal margin (n = 30) | 0 | 0 | 30 | 0 | 0 | 0 | 30 | 0 | 30 | 0 | 0 | 30 | 0 |