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Table 4 Cox regression analysis for time to Overlap/Marginal failure (Near misses)

From: A retrospective, deformable registration analysis of the impact of PET-CT planning on patterns of failure in stereotactic body radiation therapy for recurrent head and neck cancer

 

Overall Cohort (n = 96)

Definitive SBRT Subgroup (n = 89)

 

Univariate

Multivariate

Univariate

Multivariate

 

p

HR (95% CI)

p

HR (95% CI)

p

HR (95% CI)

p

HR (95% CI)

PET-CT Planning

0.042

0.48 (0.23, 0.98)

0.042

0.48 (0.23, 0.98)

0.012

0.40 (0.19, 0.82)

0.009

0.40 (0.19, 0.79)

Tumor volume (5 cc increase)

0.415

0.98 (0.92, 1.03)

0.323

Not entered

0.514

0.98 (0.92, 1.04)

0.605

Not entered

Cetuximab with SBRT

0.304

0.70 (0.35, 1.39)

0.337

Not entered

0.089

0.54 (0.27, 1.10)

0.066

0.51 (0.25, 1.04)

Interval from previous radiation to recurrence (3 months increase)

 

0.512

0.99 (0.96, 1.02)

0.604

Not entered

0.596

0.99 (0.96, 1.02)

0.963

Not entered

  1. Abbreviations: SBRT = stereotactic body radiation therapy, HR = hazard ratio for failure, CI = confidence interval.