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Figure 5 | Head & Neck Oncology

Figure 5

From: Radioimmunotherapy of experimental head and neck squamous cell carcinoma (HNSCC) with E6-specific antibody using a novel HPV-16 positive HNSCC cell line

Figure 5

Radioimmunotherapy of 2A3 tumors in mice. Mice with tumors measuring 0.5-0.7 cm in diameter were randomized into groups of five. The groups were treated IP with either: 200 μCi 188Re-C1P5 mAb, matching amount (6 μg) of "cold" C1P5 mAb; or left untreated. Mice were observed for tumor growth and survival for 15 days. The experiment was performed twice. The differences in the tumor sizes between 188Re-C1P5 mAb and untreated group were significant (P < 0.05) for all time points; the differences in the tumor sizes between 188Re-C1P5 mAb and "cold" C1P5 mAb group were significant (P < 0.05) for Day 3-9 time points.

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Head & Neck Oncology

ISSN: 1758-3284