Figure 2
From: Vascular mimicry in cultured head and neck tumour cell lines
Substrate directed growth of common tumour cell lines on matrigel, a collagen basement membrane analogue, resulted in significant growth and vascular channel formation when compared to growth on standard laboratory culture plastic, (P < 0.001). Furthermore the magnitude of this effect was reduced by the use of specific anti-endothelial antibodies, (P < 0.001). Graph showing fold increase in growth area compared to "standard" culture on laboratory Petri dishes. The Cell lines used were HN2b (head and neck SCC), DU145 (Prostate cancer), HCT116 (Colonic cancer) and HUVEC (Human Endothelial cells).