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Table 1 Studies regarding blood transfusion in head and neck cancer patients

From: An evaluation of the preoperative hemoglobin level as a prognostic factor for oral squamous cell carcinoma

Author

Patients (n)

Location

Outcome

Results

Böck[24]

174

(141 with transfusion)

Larynx/hypopharynx

Recurrence, survival, infection

No influence

Jones[25]

90

(46 with transfusion)

Head and neck

Recurrence

No influence

Ell[26]

240

(113 with transfusion)

Larynx

Survival

No influence

Woolley[27]

143

(99 with tranfusion)

Head and neck

Recurrence

P < 0.009

Von Doersten[28]

104

(51 with transfusion)

Head and neck

Recurrence, infection

No influence

Schuller[17]

217

(132 with transfusion)

Head and neck

Survival

No influence

Barra[29]

207

(152 with transfusion)

Head and neck

Survival

P < 0.05

Alun-Jones[30]

69

(38 with transfusion)

Larynx

Survival

P < 0.05

Sturgis[14]

61

(25 with transfusion)

Head and neck

Recurrence

Influence

(48% with transfusion; 24% without transfusion)

Leon[31]

269

(86 with transfusion)

Larynx

Recurrence

No influence

Moir[32]

165 (60 with transfusion)

Head and neck

Recurrence

P < 0.04

Taniguchi[15]

105

(64 with transfusion)

Oral cavity

Survival

P < 0.01

Szakmany[33]

559

(437 with transfusion)

Oral cavity/

Oropharyngeal

Recurrence,

survival

≥3 units influence

Fenner[16]

223

Oral cavity

Survival

No influence

  1. Studies involving the effects of blood transfusion in head and neck cancer show inconsistent results