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Table 2 Characteristics, presentations, and outcome of patients with sinonasal moderately differentiated (MDNEC) and poorly differentiated (PDNEC) neuroendocrine carcinoma

From: Sinonasal neuroendocrine carcinoma: impact of differentiation status on response and outcome

Characteristic

MDNEC

PDNEC

Demographics

  

   Age at presentation

47.6 (22-67)

50 (24-78)

   M:F ratio

5:2

6:7

Major Presenting Symptoms

  

   Congestion/Sinusitis

3 (43%)

7 (54%)

   Epistaxis

3 (43%)

3 (23%)

   Hearing loss

1 (14%)

0

   Neck mass

0

2 (15%)

Stage

  

   I

1 (14%)

0

   II

0

2 (15%)

   III

0

1 (8%)

   IV

5 (71%)

9 (69%)

DFS

  

   Ch + RT

11 (mon)

7.6 (mon)

   RT + Surgery

63 (mon)

16.0 (mon)

  1. • Ch: Chemotherapy
  2. • MDNEC: Moderately differentiated
  3. • PDNEC: Poorly differentiated
  4. • RT: Radiotherapy