Table 1 Modern methods of oral cytology for oral squamous cell carcinoma
From: Oral squamous cell cancer: early detection and the role of alcohol and smoking
Classification | Analytic method | Markers |
|---|---|---|
Cytomorphometry | Conventional cytologic diagnosis | Cell morphology |
| Â | Computer-assisted image | Cell morphology |
| Â | analysis (OralCDx) | Â |
DNA analysis | DNA image cytometry | DNA ploidy, DNA methylation |
Optical diagnosis | Autofluorescence | Flavin, tryptophan, elastin, |
| Â | Â | collagen (endogenous fluorophores) |
| Â | Photodynamic diagnosis | 5-Aminolevulinic acid |
| Â | Â | Photofrin |
| Â | Immunophotodiagnosis antibody targeting | EGFR |