Skip to main content

Table 6 HPV by PCR, p16 by IHC, c-MET by IHC are not associated with disease control

From: The association between EGFR variant III, HPV, p16, c-MET, EGFR gene copy number and response to EGFR inhibitors in patients with recurrent or metastatic squamous cell carcinoma of the head and neck

 

Best Response

 

Progressive Disease

Disease Control (Partial Response or Stable Disease)

 

HPV PCR negative

14 (50%)

14 (50%)

P = 0.86

HPV PCR positive

9 (47%)

10 (53%)

(Chi-square)

P16 IHC negative

14 (47%)

16 (53%)

P = 0.67

P16 IHC positive

8 (53%)

7 (47%)

(Chi-square)

c-MET IHC < or = 2

9 (56%)

7 (44%)

P = 0.39

c-MET IHC >2

12 (43%)

16 (57%)

(Chi-square)