Head & Neck Oncology

Table 4 Differentiation, pTNM, invasive front, status of surgical margin and recurrence vs. cause of death

From: Clinicopathological parameters, recurrence, locoregional and distant metastasis in 115 T1-T2 oral squamous cell carcinoma patients

	Cause of death						Fisher's
	Alive (%)	Cardio-respiratory failure (%)	Pneumonia (%)	Regional met (%)	Distant met (%)	Total
Differentiation
Well	24 (28.9)	3 (60.0)	3 (50.0)	1 (10.0)	1 (9.1)	32
Moderate	47 (56.6)	2 (40.0)	3 (50.0)	2 (20.0)	6 (54.5)	60
Moderate-poorly	8 (9.6)	0 (0.0)	0 (0.0)	2 (20.0)	1 (9.1)	11
Poorly	4 (4.8)	0 (0.0)	0 (0.0)	5 (50.0)	3 (27.3)	12	0.001
pTNM
T1N0M0	53 (63.9)	2 (40.0)	2 (33.3)	0 (0.0)	1 (9.1)	58
T2N0M0	20 (24.1)	1 (20.0)	2 (33.3)	0 (0.0)	0 (0.0)	23
T1N1M0	4 (4.8)	0 (0.0)	0 (0.0)	1 (10.0)	1 (9.1)	6
T2N1M0	2 (2.4)	1 (20.0)	1 (16.7)	2 (20.0)	0 (0.0)	6
T1N2aM0	1 (1.2)	0 (0.0)	0 (0.0)	3 (30.0)	2 (18.2)	6
T2N2aM0	0 (0.0)	1 (20.0)	1 (16.7)	2 (20.0)	5 (45.5)	9
T1N2bM0	0 (0.0)	0 (0.0)	0 (0.0)	1 (10.0)	0 (0.0)	1
T2N2bM0	1 (1.2)	0 (0.0)	0 (0.0)	1 (10.0)	1 (9.1)	3
T1N2cM0	1 (1.2)	0 (0.0)	0 (0.0)	0 (0.0)	1 (9.1)	2
T2N2cM0	1 (1.2)	0 (0.0)	0 (0.0)	0 (0.0)	0 (0.0)	1	<0.001
IF, cohesive	64 (78.0)	5 (6.1)	5 (6.1)	5 (6.1)	3 (3.7)	82
IF, non-cohesive	19 (57.6)	0 (0.0)	1 (3.0)	5 (15.2)	8 (24.2)	33	0.002
Dys. At Margin	33 (62.3)	1 (1.9)	2 (3.8)	8 (15.1)	9 (17.0)	53	0.005
Lymphvascular Invasion	13 (46.4)	1 (3.6)	2 (7.1)	6 (21.4)	6 (21.4)	28	0.002
Nerve Invasion	5 (41.7)	0 (0.0)	0 (0.0)	3 (25.0)	4 (33.3)	12	0.011
B/C Invasion	2 (40.0)	0 (0.0)	0 (0.0)	1 (20.0)	2 (40.0)	5	0.131
SD present	49 (68.1)	3 (4.2)	3 (4.2)	7 (9.7)	10 (13.9)	72	0.271
Tumour clearance	82 (76.6)	5 (4.7)	5 (4.7)	6 (5.6)	9 (8.4)	107	<0.001
Recurrence	19 (44.2)	2 (4.7)	1 (2.3)	10 (23.3)	11 (25.6)	43	<0.001
Total	83	5	6	10	11

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