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Table 1 Statistical association of clinical factors and HPV status

From: Low prevalence of Human Papillomavirus in oral cavity carcinomas

Category

Variable

Patients (#)

HPV + (%)

p-value

Age

< = 40

22

1 (4.5)

0.02

 

>40 and <60

28

10 (35.7)

 
 

> = 60

42

8 (19)

 

Sex

F

28

4 (14.3)

0.32

 

M

64

15 (23.4)

 

Smoking

Y

53

11 (20.8)

0.59

 

N

32

6 (18.8)

 
 

Former

5

0 (0)

 

Alcohol

Y

46

9 (19.6)

0.47

 

N

19

2 (10.5)

 
 

Former

6

0 (0)

 
 

Other

18

5 (27.8)

 

Stage

I

6

0 (0)

0.12

 

II

22

1 (4.5)

 
 

III

21

5 (23.8)

 
 

IV

40

10 (25)

 

Tumor Differentiation

Well

1

0 (0)

0.51

 

Moderately

68

12 (17.6)

 
 

Poorly

18

5 (27.8)

 
 

Other

5

2 (40)

 

Site

Tongue

29

1 (3.4)

< 0.0001

 

FOM

8

1 (12.5)

 
 

FOM+Tongue

6

0 (0)

 
 

Oropharynx (Base of Tongue)

22

16 (72.7)

 
 

Larynx/Pharynx/Nasopharynx

17

1 (5.9)

 
 

Other

10

0 (0)

 

Node

+

43

15 (34.9)

< 0.0001

 

-

46

1 (2.2)

 

Outcome

Alive

83

17 (20.5)

0.24

 

Dead

7

0 (0)

 

HPV

+

19

  
 

-

73

  
  1. Clinical categories and the variables were examined for significant associations with HPV status. Statistical significance was assessed by Fisher's exact and Pearson's chi-square tests (p ≤ 0.05). M - Male; F -- Female; Y -- Yes; N -- No; FOM -- Floor of Mouth. Unknown values were not included in analysis.