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Table 6 Association of p53 aberrations and exposure index

From: p53 in head and neck cancer: Functional consequences and environmental implications of TP53mutations

Exposure

Indexa

Positive p53 IHC

(number of patients)

TP53mutation

(number of patients)

0

1/2

 

2/2

 

1

-

3/8 (37.5%)

-

3/8 (37.5%)

2

2/6

 

1/6

 

3

1/4

 

3/4

 

4

4/9

10/20 (50%)

3/9

9/20 (45%)

5

5/7

 

3/7

 

6

4/5

 

5/5

 

7

3/4

8/10 (80%)

2/4

8/10 (80%)

8

1/1

 

1/1

 
  1. a tobacco, alcohol, chemical/dust exposure, see table 2