Table 4 Summary of mutations
From: p53 in head and neck cancer: Functional consequences and environmental implications of TP53mutations
Anatomic site | Number of cases | Total number (%) of mutated cases | Total number of TP53mutations | TP53mutation frequency in different exons | |||
|---|---|---|---|---|---|---|---|
Exon 5 | Exon 6 | Exon 7 | Exon 8 | ||||
larynx | 24 | 13/24 (54%) | 19 | 9/19 (47%) | 3/19 (16%) | 5/19 (26%) | 2/19 (10.5%) |
pharynx | 6 | 4/6 (67%) | 5 | 2/5 (40%) | 0 | 3/5 (60%) | 1/5 (20%) |
oral cavity | 14 | 9/14 (64%) | 14 | 6/14 (43%) | 0 | 4/14 (29%) | 4/14 (29%) |
nose & sinuses | 2 | 0 | 0 | 0 | 0 | 0 | 0 |
all sites | 46 | 26/46 (56.5%) | 39 | 17/39 (43%) | 3/39 (8%) | 12/39 (31%) | 7/39 (18%) |