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Table 4 Summary of mutations

From: p53 in head and neck cancer: Functional consequences and environmental implications of TP53mutations

Anatomic site Number of cases Total number (%) of mutated cases Total number of
TP53mutations
TP53mutation frequency in different exons
     Exon 5 Exon 6 Exon 7 Exon 8
larynx 24 13/24 (54%) 19 9/19 (47%) 3/19 (16%) 5/19 (26%) 2/19 (10.5%)
pharynx 6 4/6 (67%) 5 2/5 (40%) 0 3/5 (60%) 1/5 (20%)
oral cavity 14 9/14 (64%) 14 6/14 (43%) 0 4/14 (29%) 4/14 (29%)
nose & sinuses 2 0 0 0 0 0 0
all sites 46 26/46 (56.5%) 39 17/39 (43%) 3/39 (8%) 12/39 (31%) 7/39 (18%)