Table 1 Clinicopathological variables and p53 status in patients of head and neck carcinoma
From: p53 in head and neck cancer: Functional consequences and environmental implications of TP53mutations
Patient characteristics | n | TP53mutation n/n(%) | p53 ihc positive n/n(%) |
|---|---|---|---|
All patients | 46 | 26/46 (56.5%) | 24/46 (52.2%) |
Sex | |||
Male | 31 | 18/31 (58.1%) | 19/31 (61.3%) |
Female | 15 | 8/5 (53.3%) | 5/15 (33.3%) |
Age, years | |||
≤ 39 | 3 | 3/3 (100.0%) | 2/3 (66.7%) |
40-65 | 23 | 13/23 (56.5%) | 10/23 (43.5%) |
≥ 66 | 20 | 10/20 (50.0%) | 12/20 (60.0%) |
Anatomical diagnosis | |||
Oral cavity | 14 | 9/14 (64.3%) | 4/14 (28.6%) |
Larynx | 24 | 13/24 (54.2%) | 19/24 (79.2%) |
Pharynx | 6 | 4/6 (66.7%) | 1/6 (16.7%) |
Others | 2 | 0/2 (0%) | 0/2 (0%) |
Grade | |||
Grade 1 | 10 | 5/10 (50.0%) | 5/10 (50.0%) |
Grade 2 | 29 | 17/29 (58.6%) | 14/29 (48.3%) |
Grade 3 | 7 | 4/7 (57.1%) | 5/7 (71.4%) |
TNM classification | |||
T1-2 | 29 | 14/29 (48.3%) | 17/29 (58.6%) |
T3-4 | 17 | 12/17 (70.6%) | 7/17 (41.2%) |
N0 | 23 | 14/23 (60.9%) | 13/23 (56.5%) |
N+ | 23 | 12/23 (52.2%) | 11/23 (47.8%) |
Stage | |||
I | 6 | 4/6 (66.7%) | 3/6 (50.0%) |
II | 9 | 4/9 (44.4%) | 7/9 (77.8%) |
III | 20 | 11/20 (55.0%) | 10/20 (50.0%) |
IV | 11 | 7/11 (63.6%) | 4/11 (36.4%) |