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Table 1 Clinicopathological variables and p53 status in patients of head and neck carcinoma

From: p53 in head and neck cancer: Functional consequences and environmental implications of TP53mutations

Patient characteristics n TP53mutation n/n(%) p53 ihc positive n/n(%)
All patients 46 26/46 (56.5%) 24/46 (52.2%)
Sex
   Male 31 18/31 (58.1%) 19/31 (61.3%)
   Female 15 8/5 (53.3%) 5/15 (33.3%)
Age, years
   ≤ 39 3 3/3 (100.0%) 2/3 (66.7%)
   40-65 23 13/23 (56.5%) 10/23 (43.5%)
   ≥ 66 20 10/20 (50.0%) 12/20 (60.0%)
Anatomical diagnosis
   Oral cavity 14 9/14 (64.3%) 4/14 (28.6%)
   Larynx 24 13/24 (54.2%) 19/24 (79.2%)
   Pharynx 6 4/6 (66.7%) 1/6 (16.7%)
   Others 2 0/2 (0%) 0/2 (0%)
Grade
   Grade 1 10 5/10 (50.0%) 5/10 (50.0%)
   Grade 2 29 17/29 (58.6%) 14/29 (48.3%)
   Grade 3 7 4/7 (57.1%) 5/7 (71.4%)
TNM classification
   T1-2 29 14/29 (48.3%) 17/29 (58.6%)
   T3-4 17 12/17 (70.6%) 7/17 (41.2%)
   N0 23 14/23 (60.9%) 13/23 (56.5%)
   N+ 23 12/23 (52.2%) 11/23 (47.8%)
Stage
   I 6 4/6 (66.7%) 3/6 (50.0%)
   II 9 4/9 (44.4%) 7/9 (77.8%)
   III 20 11/20 (55.0%) 10/20 (50.0%)
   IV 11 7/11 (63.6%) 4/11 (36.4%)