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Figure 2 | Head & Neck Oncology

Figure 2

From: Immunohistochemical analysis of undifferentiated and poorly-differentiated head and neck malignancies at a tertiary hospital in Nigeria

Figure 2

Photomicrographs showing the Immunohistochemical profile of a neuroendocrine carcinoma. The haematoxylin and eosin (H&E) section shows highly pleomorphic cells with nuclei vessiculation and prominent nucleoli disposed in islands. Moderate immunopositivity of neurone specific enolase (NSE) for epithelioid-like cells is noted. Epithelial markers (AE1 and AE3) are strongly positive and there is a non-specific staining pattern of epithelial cells and lymphocytes with vimentin (VIM). The tumour is negative for desmin (DES) and leukocyte common antigen (LCA). All immunohistochemical sections were counterstained with hematoxylin. (X400)

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