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Table 4 Clinicopathological variables affecting overall survival (univariate analysis).

From: Prognostic Significance of Nuclear Survivin Expression in Resected Adenoid Cystic Carcinoma of the Head and Neck

Variable

P-value (chi-square)

Stage (I, II/III, IV)

0.001*

Lymph node metastasis

0.014*

Tumor size (≤ 3 cm/> 3 cm)

0.036*

Growth pattern (tubular, cribriform/solid)

0.806

Tumor grade (well, moderately/poorly)

0.235

Perineural invasion

0.377

Perivascular invasion

0.926

Lymphatic invasion

0.569

C-survivin (high/low)

0.160

N-survivin (high/low)

0.035*

Bcl-2 (positive/negative)

0.986

Ki-67 (positive/negative)

0.872

p53 (positive/negative)

0.957

  1. * statistically significant (P < 0.05)
  2. cytoplasmic survivin
  3. nuclear survivin