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Table 5 Meta-analyses of association between p53 mutations, p16 and HPV

From: Meta-analysis of the impact of human papillomavirus (HPV) on cancer risk and overall survival in head and neck squamous cell carcinomas (HNSCC)

  

Before outlier exclusion

After outlier exclusion

Outcome

Marker

No. of Studies

Adjusted OR (95% CI)

No. of Studies

Adjusted OR (95% CI)

HPV positive

p53 (mutated)

4

0.21(0.04-0.38)

4

0.21(0.04-0.38)

     

P = 0.015

HPV positive

p16

2

5.02(1.08-8.97)

1

3.00(0.90-9.70)

 

IHC

   

p = 0.181