Figure 3

Scatter plots of the image features and corresponding ROC curves for classification algorithms. (a) Scatter plot of the normalized blue MFI for all sites measured by consensus clinical impression. (b) ROC curve for diagnostic algorithm based on normalized blue MFI to differentiate between non-neoplastic sites (Normal, LR and OSF) and neoplastic sites (HR and Cancer). Measurements with melanosis were excluded from algorithm development and testing. The open circle on the ROC curve indicates the Q-point. (c) Scatter plot of the normalized ratio of red to green MFI for all sites measured by consensus clinical impression. (d) ROC curve for diagnostic algorithm based on normalized ratio of red to green MFI to differentiate between non-neoplastic sites (Normal, LR and OSF) and neoplastic sites (HR and Cancer). Measurements with melanosis were excluded from algorithm development and testing. The open circle on the ROC curve indicates the Q-point.