Table 2 Selected up-regulated genes identified in HNSCC*
From: Identification of potential therapeutic targets in human head & neck squamous cell carcinoma
GeneBank Access ID | Gene Symbol & Annotation | Log2 Fold Difference** |
|---|---|---|
Immune Response | ||
L19686 | MIF, macrophage migration inhibitory factor | 3.1 |
M13560 | CD74, CD74 antigen | 2.6 |
M63438 | IGKC, immunoglobulin kappa constant | 1.9 |
J03909 | IFI30, interferon, gamma-inducible protein 30 | 1.5 |
AJ251549 | IL26, interleukin 26 | 1.4 |
L33930 | CD24, CD24 antigen | 1.4 |
X16302 | IGFBP2, insulin-like growth factor binding protein 2 | 1.4 |
S75725 | IGFBP7, insulin-like growth factor binding protein 7 | 1.4 |
Cell Growth, Maintenance/Cell cycle Regulation | ||
Y00503 | KRT19, keratin 19 | 3.9 |
U43901 | LAMR1, laminin receptor 1 | 3.2 |
AL031670 | FTL, ferritin, light polypeptide | 2.5 |
J00124 | KRT14, keratin 14 | 2.5 |
X07696 | KRT 15, keratin 15 | 2.4 |
X95404 | CFL1, cofilin 1 | 2.3 |
D13627 | CCT8, chaperonin subunit 8 | 2.1 |
AF026291 | CCT4, chaperonin subunit 4 | 2.0 |
Z68228 | JUP, junction plakoglobin | 1.9 |
M26326 | KRT18, keratin 18 | 1.8 |
L42583 | KRT6C, keratin 6C | 1.7 |
Translation and Protein Synthesis | ||
AK001313 | RPLP0, ribosomal protein LP0 | 4.1 |
L06499 | RPL37A, ribosomal protein L37A | 3.9 |
U73824 | EIF4G2, translation initiation factor 4 gamma 2 | 3.2 |
M64241 | RPL10, ribosomal protein L10 | 3.2 |
X69150 | RPS18, ribosomal protein S18 | 3.1 |
M84711 | RPS 3A, ribosomal protein S3A | 3.0 |
NM_000996 | RPL35A, ribosomal protein L35A | 3.0 |
U25789 | RPL21, ribosomal protein L21 | 2.9 |
L11566 | RPL18, ribosomal protein L18 | 2.8 |
Z21507 | EEF1D, eukaryotic translation elongation factor 1D | 2.3 |
AL117412 | EIF4A2, eukaryotic translation initiation factor 4A | 2.2 |
AC002544 | EIF3S8, eukaryotic translation initiation factor 3, subunit 8 | 2.1 |
Metabolism | ||
Z23090 | HSPB1, heat shock 27 kDa protein | 4.2 |
M94856 | FABP5, fat acid binding protein 5 | 3.7 |
NM_021130 | PPIA, peptidylprolyl isomerase A (cyclophilin A) | 2.9 |
M26252 | PKM2, pyruvate kinase, muscle | 2.6 |
NM_001679 | ATP1B3, ATP synthase Na+/K+ transporting, beta 3 | 2.6 |
AF061735 | ATP5H, ATP synthase H+ transporting subunit | 2.1 |
Y00483 | GPX1, glutathione peroxidase 1 | 2.0 |
AL021546 | COX6A1, cytochrome c oxidase subunit VI a1 | 1.9 |
X13923 | COX6B, cytochrome c oxidase subunit VI b | 1.8 |
X13794 | LDHB, lactate dehydrogenase B | 1.7 |
Z85996 | CDKN1A, cyclin-dependent kinase inhibitor 1A | 1.7 |
M60483 | PPP2CA, protein phosphatase 2 catalytic subunit | 1.7 |
Y13936 | PPM1G, protein phosphatase 1G | 1.6 |
U09813 | ATP5G3, ATP synthase H+ transporting subunit | 1.6 |
D29011 | PSMB5, proteasome subunit, beta 5 | 1.6 |
AF047181 | NDUFB5, NADH dehydrogenase beta subcomplex 5 | 1.5 |
Ion Binding Proteins | ||
Y07755 | S100A2, S100 calcium binding protein A2 | 3.6 |
D38583 | S100A11, S100 calcium binding protein A11 | 2.4 |
NM_020672 | S100A14, S100 calcium binding protein A14 | 1.9 |
X99920 | S100A13, S100 calcium binding protein A13 | 1.2 |
Others | ||
M14328 | ENO1, enolase 1 | 3.3 |
M26880 | UBC, ubiquitin C | 3.2 |
S54005 | TMSB10, thymosin, beta 10 | 2.8 |
D87953 | NDRG1, M-myc downstream regulated gene 1 | 2.4 |
M36981 | NME2, non-metastatic cells 2 protein | 2.3 |
AF055008 | GRN, granulin | 2.3 |
X57348 | SFN, stratifin | 2.3 |
U46751 | SQSTM1, sequestosome 1 | 2.2 |
X67951 | PRDX1, peroxiredoxin 1 | 2.1 |
X65607 | MT1X, metallothionein 1X | 1.5 |
X84709 | FADD, Fas associated death domain | 1.2 |